Guides
Weight management guides
Evidence-based guidance on how treatment, food and movement interact. Every guide opens with a direct answer, cites its sources, and is written to be useful whether or not you are on treatment.
How GLP-1 Medication Works
GLP-1 medications work by mimicking a hormone the gut releases after eating. They slow the rate at which the stomach empties and act on appetite centres in the brain, so hunger falls and fullness lasts longer after a meal.
Read guideManaging Side Effects
The most common side effects of GLP-1 weight loss treatments are gastrointestinal: nausea, diarrhoea or constipation, vomiting and indigestion. They are usually mild, most noticeable in the days after a dose increase, and tend to settle as the body adapts.
Read guideDosage and Titration
Weight loss injections start at a low dose that is increased in stages, a process called titration. Tirzepatide begins at 2.5 mg once weekly for four weeks, moves to 5 mg, then rises in 2.5 mg increments no sooner than every four weeks, to a maximum of 15 mg.
Read guideNutrition on weight loss treatment
On weight loss injections the constraint is not willpower, it is capacity. Appetite suppression means you will eat considerably less, so what you do eat has to carry more.
Read guideExercise and muscle retention
Resistance training twice a week is the priority, not cardio. On weight loss treatment the calorie deficit is already handled by appetite suppression, so exercise is not there to burn energy.
Read guide