Prescription only
WegovySemaglutide · GLP-1 receptor agonist
What is Wegovy?
Wegovy is the brand name for semaglutide 2.4 mg, a once-weekly injection licensed in the UK for weight management. It acts on the GLP-1 receptor, reducing appetite and slowing gastric emptying so that people feel full sooner and for longer. It is prescription-only and used alongside dietary and activity changes, not instead of them.
Licensed for weight management
Wegovy is licensed in the UK for weight management alongside a reduced-calorie diet and increased physical activity. It contains semaglutide at 2.4 mg, a higher dose than Ozempic, which contains the same molecule but is licensed for type 2 diabetes.
At a glance
- Active ingredient
- Semaglutide
- Drug class
- GLP-1 receptor agonist
- Administration
- Once-weekly subcutaneous injection
- Manufacturer
- Novo Nordisk
- Dose range
- 0.25 mg – 2.4 mg weekly
Treatment options and pricing are discussed after clinical assessment, as required for prescription-only medicines.
Start your assessmentHow Wegovy works
Semaglutide mimics glucagon-like peptide-1, a hormone released by the gut after eating. Sustaining that signal across a week rather than minutes is what produces a therapeutic effect.
It slows the rate at which the stomach empties, so fullness after a meal lasts longer, and acts on appetite centres in the brain to reduce hunger.
Unlike tirzepatide, which acts on both GIP and GLP-1 receptors, semaglutide acts on GLP-1 alone. In the SURMOUNT-5 head-to-head trial the dual mechanism produced greater average weight reduction, though individual response and tolerability vary.
Who it may suit
May be considered for
- Adults meeting the BMI thresholds set out in NICE guidance, assessed individually
- People whose weight is associated with conditions such as type 2 diabetes, hypertension or obstructive sleep apnoea
- People able to commit to dietary and activity change alongside treatment
Not suitable if
- Personal or family history of medullary thyroid carcinoma, or Multiple Endocrine Neoplasia syndrome type 2
- Pregnancy, breastfeeding, or planning to conceive
- Previous hypersensitivity to semaglutide
- History of pancreatitis, requiring individual assessment
Dosage and titration
| Step | Dose | Timing |
|---|---|---|
| Starting dose | 0.25 mg | Once weekly for 4 weeks |
| Step 2 | 0.5 mg | Weeks 5 to 8 |
| Step 3 | 1 mg | Weeks 9 to 12 |
| Step 4 | 1.7 mg | Weeks 13 to 16 |
| Maintenance | 2.4 mg | From week 17 |
Escalation takes 16 weeks to reach the maintenance dose, with four weeks at each step. A prescriber may hold a dose longer where side effects warrant it. Dose decisions belong with your prescriber and should never be self-directed.
Side effects
Common Usually mild
- Nausea, most noticeable after a dose increase
- Diarrhoea or constipation
- Vomiting
- Indigestion, reflux and reduced appetite
- Headache and fatigue
- Injection-site reactions
Serious Seek advice
- Pancreatitis, severe, persistent abdominal pain that may radiate to the back
- Gallbladder problems, including gallstones
- Severe or persistent vomiting leading to dehydration
- Allergic reaction, swelling of the face, lips or throat
- Low blood sugar, particularly alongside insulin or a sulfonylurea
As with other GLP-1 receptor agonists, rodent studies showed thyroid C-cell tumours; whether this occurs in humans is unknown, which is why a personal or family history of medullary thyroid carcinoma is a contraindication. The MHRA has an ongoing safety review into serious harms including pancreatitis across this drug class.
Interactions
- Oral medicines: delayed gastric emptying can alter absorption. Tell your prescriber everything you take, including over-the-counter medicines.
- Insulin and sulfonylureas: risk of low blood sugar increases and doses may need adjusting.
- Oral contraceptives: discuss contraception with your prescriber before starting treatment.
- Alcohol: can worsen nausea and affect blood glucose.
Storage
Store in a refrigerator at 2–8°C in the original carton, protected from light. Do not freeze. Follow the patient information leaflet supplied with your pen for storage after first use and for the permitted period outside refrigeration.
How to get Wegovy, and what it costs
Wegovy is a prescription-only medicine. It cannot be bought over the counter, from a supplement retailer, or from any website that sells it without an assessment, those are not legitimate suppliers, and what arrives from them is of unverified identity and strength.
The route is the same wherever you obtain it legitimately: a clinical assessment, review by a named prescriber, and supply from a registered pharmacy only if treatment is judged appropriate for you. There is no lawful shortcut around that step, and a provider offering one is telling you something useful about itself.
Cost varies by provider, by dose and by market, and is discussed after assessment rather than advertised, prescription-only medicines cannot be promoted to the public with pricing. What you can establish before committing is whether a provider verifies your information properly, who the named prescriber is, and what follow-up is included.
- 01Complete a clinical assessment
Medical history, current medication, BMI and any weight-related conditions. Around five minutes.
- 02Independent verification
Weight-management medicines are classed as high-risk, so a prescriber must verify your information rather than rely on the form alone.
- 03Prescriber decision
A named clinician decides whether treatment is appropriate. Some assessments end without treatment.
- 04Supply and follow-up
Dispensed by a registered pharmacy, with scheduled reviews to manage dose changes and side effects.
Where to buy Wegovy in the UK
Three lawful routes. The NHS, where access is restricted to specialist weight-management services and criteria are tight. A registered online pharmacy that assesses you first. Or a high street pharmacy against a private prescription from a prescriber who has assessed you.
Each of those routes puts an assessment in front of the supply, and that is what separates them from everything else. A website that will sell you Wegovy without assessing you is operating outside the law, and the contents of what arrives cannot be verified.
You can check a UK pharmacy before you buy. Registered pharmacies appear on the General Pharmaceutical Council register, and registered online pharmacies display the MHRA distance selling logo as a link back to the regulator. A logo that is only a picture is not a registration.
How to get a Wegovy prescription
A clinical assessment first, covering medical history, current medication, height and weight, and any weight-related conditions. A prescriber then reviews it independently and decides whether Wegovy is appropriate.
Weight-management medicines are classed as high-risk, so the prescriber has to verify what you have reported rather than accept the form as submitted. That means a photograph, a video call, or contact with your GP. A provider that omits that step is not following the regulator's rules.
The answer can be no, and some assessments end without a prescription. That is the process working.
How to identify a licensed Wegovy supplier
Four checks. The pharmacy is on the GPhC register. It names its superintendent pharmacist. It shows the MHRA distance selling logo as a working link. And it will not supply without an assessment.
The signals to walk away from are consistent: an advertised price, no assessment, no named prescriber, payment by bank transfer or cryptocurrency, or plentiful stock at a time when legitimate pharmacies are reporting supply constraints.
Sellers on social media, marketplaces and messaging apps are not licensed suppliers whatever their listing says. Falsified semaglutide has been found in UK supply chains and seized by the MHRA, and counterfeit packaging is usually better than people expect.
Can you buy Wegovy online?
Only from a registered pharmacy, and only after a clinical assessment and a prescription. Searching "wegovy buy online" returns plenty of sites willing to skip both; none of them is a lawful supplier, and what arrives from them cannot be verified for identity, strength or sterility.
A legitimate online pharmacy looks different in one specific way: it will not let you reach a checkout before a prescriber has decided. If you can add Wegovy to a basket, you are not on a pharmacy site.
What Wegovy reviews do and do not tell you
Searching "wegovy reviews" mostly returns individual accounts, and those are worth reading for what treatment feels like week to week: nausea after a dose increase, appetite changes, what people found manageable.
What reviews cannot tell you is whether Wegovy is appropriate for you. Response varies considerably between people, and a review is a sample of one with no information about the reader. The trial data on this page is the part that generalises; the reviews are the part that does not.
Wegovy price in the UK, and why no price is shown here
Cost depends on the dose, and the dose escalates over the first four months, so any single figure would be wrong for most people for most of that period. It also varies by provider and by market.
The reason no figure appears on this page is specific: prescription-only medicines cannot be advertised to the public in the UK, and a published price is advertising. You are quoted after assessment, once the dose is known. A site that shows you a price for Wegovy before assessing you is telling you it does not follow that rule.
What is worth comparing before you commit is what the price includes. Whether follow-up reviews are covered, whether dose increases cost more, whether prescriber contact is charged separately, and what happens if you stop.
Clinical evidence
What the trials showed
Mean weight reduction of approximately 14.9% at 68 weeks
In adults with obesity or overweight without type 2 diabetes, semaglutide 2.4 mg produced a mean body weight reduction of around 14.9% over 68 weeks, alongside lifestyle intervention.
Lower mean reduction than tirzepatide, head to head
In the first direct comparison, published in the New England Journal of Medicine, semaglutide produced a 13.7% mean reduction against 20.2% for tirzepatide across 72 weeks in 751 adults. Averages describe a trial population, not an individual.
Wegovy questions, answered
Where can I get Wegovy?
From a registered pharmacy, once a prescriber has assessed you. In practice that is the NHS if you meet the specialist service criteria, a registered online pharmacy that assesses you first, or a high street pharmacy against a private prescription. Check the pharmacy on the GPhC register before ordering.
Can I order Wegovy online safely?
Yes, provided the pharmacy is GPhC-registered and assesses you before it supplies. The test is simple: if you can pay for Wegovy without an assessment, the seller is not operating lawfully. Registered online pharmacies display the MHRA distance selling logo as a link to their regulator entry.
Where can I buy Wegovy?
Only from a registered pharmacy, after a clinical assessment and a prescription from a named prescriber. Wegovy is prescription-only and cannot be bought over the counter. Any site supplying it without assessing you is not a legitimate pharmacy.
How much does Wegovy cost?
Cost varies by provider and dose and is discussed after assessment rather than advertised, since prescription-only medicines cannot be promoted to the public with pricing. What you can check beforehand is whether the provider verifies your information, names its prescriber, and includes follow-up.
What is Wegovy?
Wegovy is the brand name for semaglutide 2.4 mg, a once-weekly injection licensed in the UK for weight management. It reduces appetite and slows gastric emptying by acting on the GLP-1 receptor, and is used alongside dietary and activity changes.
Is Wegovy the same as Ozempic?
Both contain semaglutide, but they are different products. Wegovy is dosed to 2.4 mg weekly and licensed for weight management. Ozempic is dosed up to 2 mg weekly and licensed for type 2 diabetes. They are not interchangeable, and only Wegovy is licensed for weight loss.
How long does Wegovy take to reach the full dose?
Sixteen weeks. The schedule runs 0.25 mg, 0.5 mg, 1 mg then 1.7 mg, four weeks at each step, reaching the 2.4 mg maintenance dose from week 17. A prescriber may extend any step if side effects require it.
Is Mounjaro better than Wegovy?
In the SURMOUNT-5 head-to-head trial, tirzepatide produced greater average weight reduction than semaglutide, 20.2% against 13.7% over 72 weeks. That is a population average, not a prediction for any individual, and tolerability, other conditions and existing medicines all bear on which treatment is appropriate.
Can you buy Wegovy UK, and where from?
From a GPhC-registered pharmacy, after a prescriber has assessed you. Searching "buy Wegovy UK" also returns sites that will supply without an assessment; none of those is a lawful supplier, and what arrives cannot be verified for identity, strength or sterility.
Where to get Wegovy if the NHS route is not open to you?
A registered online pharmacy that assesses you first, or a high street pharmacy against a private prescription from a prescriber who has assessed you. Both have the same step in front of them, and the question of where to get Wegovy is really the question of who is taking responsibility for the decision.
What makes a Wegovy online pharmacy UK listing genuine?
Four checks. It appears on the General Pharmaceutical Council register. It names its superintendent pharmacist. It displays the MHRA distance selling logo as a working link rather than a picture. And it will not let you reach a checkout before a prescriber has decided. Any Wegovy online pharmacy UK result missing one of those is not what it claims.
Can you get Wegovy without prescription?
No. Wegovy is a prescription-only medicine, and searching "Wegovy without prescription" returns sellers operating outside the law rather than a shortcut nobody told you about. What arrives from them has unverified identity, strength and sterility; falsified pens have been found in UK supply chains and seized by the MHRA. There is no pharmacy, in any country, that may lawfully supply it without one.
Sources
- Wegovy, Summary of Product Characteristics · electronic medicines compendium
- Semaglutide for managing overweight and obesity (TA875) · NICE
- SURMOUNT-5: tirzepatide versus semaglutide · American College of Cardiology
- Obesity, treatment · NHS
Awaiting sign-off by a named clinician.
Last updated
Related
- How to buy weight loss medication safely
- Mounjaro (tirzepatide)
- Ozempic, the diabetes licence
- Compare treatments
- Managing side effects
Eligibility is decided by a clinician, not a questionnaire. Assessment is free and takes about five minutes.